Effects of Continuous Positive Airway Pressure on Lipidaemia and High-sensitivity C-reactive Protein Levels in Non-obese patients with Coronary Artery Disease and Obstructive Sleep Apnoea

Huang, Z., Liu, Z., Zhao, Q., Luo, Q., Tang, Y.

Heart, Lung and Circulation, 2016 Jan 4 (Epub ahead of print)

PMID: 26804247


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Can Continuous Positive Airway Pressure Reduce the Risk of Stroke in Obstructive Sleep Apnea Patients? A Systematic Review and Meta-Analysis

Kim YKoo YSLee HYLee SY

PLoS One. 2016 Jan 5;11(1):e0146317. 

PMCID: PMC4701420

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Rationale and design of the Randomized Intervention with CPAP in Coronary Artery Disease and Sleep Apnea - RICCADSA trial

Peker Y, Glantz H, Thunström E, Kallryd A, Herlitz J, Ejdebäck J.

Scand Cardiovasc J. 2009 Feb;43(1):24-31. doi: 10.1080/14017430802276106

PMID: 18663661

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Occurrence and predictors of obstructive sleep apnea in a revascularized coronary artery disease cohort

Glantz H, Thunström E, Herlitz J, Cederin B, Nasic S, Ejdebäck J., Peker Y

Ann Am Thorac Soc. 2013 Aug;10(4):350-6. doi 10.1513/AnnalsATS.201211-106OC

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CPAP Tops Oxygen for Sleep Apnea

Phend, Crystal. "CPAP Tops Oxygen for Sleep Apnea." MedPage Today. N.p., 11 Jun. 2014. Web. 18 Jun. 2014.

"To tackle the cardiovascular risks from obstructive sleep apnea, continuous positive airway pressure (CPAP) was better than giving oxygen at night, and adding a weight-loss strategy may be even better in some respects for obese patients.

CPAP cut 24-hour mean arterial blood pressure by 2.8 mmHg more than did supplemental oxygen at night (P=0.02) in a high-cardiovascular-risk population, Daniel J. Gottlieb, MD, MPH, of Brigham and Women's Hospital in Boston, and colleagues found in the HeartBEAT trial.

In a second trial of obese patients with elevated C-reative protein (CRP) levels, CPAP came out similar to a weight-loss intervention or the combination of the two for reducing the inflammatory marker.

But CPAP plus weight management brought down insulin resistance, triglycerides, and blood pressure best, Julio A. Chirinos, MD, PhD, of the University of Pennsylvania in Philadelphia, and colleagues reported."

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