Marquise Brown Authentic Jersey  International Collaboration On Sleep Apnea Cardiovascular Trialists


SPIRIT statement - assistance for writing protocols

SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013, a guideline for the minimum content of a clinical trial protocol. The 33-item SPIRIT checklist is a helpful tool to ensure all clinical trial protocols describe all areas of what is planned in a standardised format

Sleep Apnea Cardiovascular Clinical Trials-Current Status and Steps Forward: The International Collaboration of Sleep Apnea Cardiovascular Trialists.

Gottlieb DJ, Craig SE, Lorenzi-Filho G, Heeley E, Redline S, McEvoy RD, Durán-Cantolla J.

Sleep. 2013 Jul 1;36(7):975-980.

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National Sleep Research Resource Launched to Promote Data Sharing


On April 1, 2014, the National Sleep Research Resource (NSRR - was opened to the scientific community. 

The National Sleep Research Resource (NSRR) funded by the NHLBI, offers free web access ( to “big data” collections of de-identified physiological signals and data elements. collected in well-characterized research cohorts and clinical trials. Users can query and search across thousands of data elements, identify those of most relevance and explore their statistical distributions.Polysomnography (PSG) recordings are available in downloadable EDF (European data format). Users can also download standard annotations and derived summary measures. The first data sets available include the over 8,000 studies from Exams 1 and 2 from the Sleep Heart Health Study (SHHS), with new data releases scheduled every quarter. The NSRR also provides open-source software for viewing and analyzing these data. Access is intended to spur hypothesis generation and testing, cross-cohort analysis of risk factors and outcomes, development of new signal processing tools, and to enhance training in clinical analysis, signal processing, epidemiological analysis, and understanding of brain and cardiopulmonay function in health and disease.

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